274 research outputs found
Realizing the Power of Extelligence: A New Business Model for Academic Publishing
The limitations of traditional academic knowledge exchange systems such as conferences and peer-reviewed journals result in discipline-based scholarship that is feudal in nature and can only dissipate as cross-disciplinary research expands. The next evolutionary step is democratic online knowledge exchange, run by the academic many rather than the publishing-oligarchic few. Using sociotechnical tools it is possible to implement an academic publishing business model that maximizes the power of âextelligenceâ, or knowledge realized through the collective gifting of information. Such a model would change the roles of journal editors and peer reviewers from knowledge gatekeepers to knowledge guides, and change the competitive yet conforming behaviors of academic researchers seeking publication to behaviors that reward collaborative activity that engages research communities in the act of knowledge exchange. We argue that socio-technical systems, social systems sitting on a technical base such as the Internet, can provide effective ways to motivate people to increase knowledge that research communities can share. By employing a hybrid of wiki, e-journal, electronic repository, micro-commenting and reputation systems for readers and writers, along with other socio-technical functions common to social computing such as social book-marking and reader recommendation, we can move from our traditional print publishing model in which prestige is established through publication in slowly produced, expensive and virtually unread journals to a vibrant, online knowledge exchange community built upon the foundations of legitimacy, transparency and freedom
Regularization Paths for Generalized Linear Models via Coordinate Descent
We develop fast algorithms for estimation of generalized linear models with convex penalties. The models include linear regression, two-class logistic regression, and multi- nomial regression problems while the penalties include ĂÂąĂĂ_1 (the lasso), ĂÂąĂĂ_2 (ridge regression) and mixtures of the two (the elastic net). The algorithms use cyclical coordinate descent, computed along a regularization path. The methods can handle large problems and can also deal efficiently with sparse features. In comparative timings we find that the new algorithms are considerably faster than competing methods.
Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of l_1 and l_2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a regularization path. We demonstrate the efficacy of our algorithm on real and simulated data sets, and find considerable speedup between our algorithm and competing methods.
Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of l1 and l2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a regularization path. We demonstrate the efficacy of our algorithm on real and simulated data sets, and find considerable speedup between our algorithm and competing methods
American Democracy in Crisis: The Challenges of Voter Knowledge, Participation, and Polarization
"American Democracy in Crisis: The Challenges of Voter Knowledge, Participation, and Polarization"â the first of a series of surveys from PRRI/The Atlantic examining challenges to democratic institutions and practicesâ finds an alarming number of Americans do not know what factors qualify people for or disqualify people from voting. The survey also finds large divides by political party, race, and ethnicity regarding the biggest problems facing the U.S. electoral system. At the same time, there is strong, bipartisan support for a range of policies that increase access to the ballot
DFSeer: A visual analytics approach to facilitate model selection for demand forecasting
Selecting an appropriate model to forecast product demand is critical to the
manufacturing industry. However, due to the data complexity, market uncertainty
and users' demanding requirements for the model, it is challenging for demand
analysts to select a proper model. Although existing model selection methods
can reduce the manual burden to some extent, they often fail to present model
performance details on individual products and reveal the potential risk of the
selected model. This paper presents DFSeer, an interactive visualization system
to conduct reliable model selection for demand forecasting based on the
products with similar historical demand. It supports model comparison and
selection with different levels of details. Besides, it shows the difference in
model performance on similar products to reveal the risk of model selection and
increase users' confidence in choosing a forecasting model. Two case studies
and interviews with domain experts demonstrate the effectiveness and usability
of DFSeer.Comment: 10 pages, 5 figures, ACM CHI 202
Risk factors for high anti-HHV-8 antibody titers (â„1:51,200) in black, HIV-1 negative South African cancer patients: a case control study
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the
development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase
risk for KS. However, the geographic distribution of HHV-8 and KS both prior to the HIV/AIDS
epidemic and with HIV/AIDS suggest the presence of an additional co-factor in the development of
KS.
Methods: Between January 1994 and October 1997, we interviewed 2576 black in-patients with
cancer in Johannesburg and Soweto, South Africa. Blood was tested for antibodies against HIV-1
and HHV-8 and the study was restricted to 2191 HIV-1 negative patients. Antibodies against the
latent nuclear antigen of HHV-8 encoded by orf73 were detected with an indirect
immunofluorescence assay. We examined the relationship between high anti-HHV-8 antibody
titers (â„1:51,200) and sociodemographic and behavioral factors using unconditional logistic
regression models. Variables that were significant at p = 0.10 were included in multivariate analysis.
Results: Of the 2191 HIV-1 negative patients who did not have Kaposi's sarcoma, 854 (39.0%)
were positive for antibodies against HHV-8 according to the immunofluorescent assay. Among
those seropositive for HHV-8, 530 (62.1%) had low titers (1:200), 227 (26.6%) had medium titers
(1:51,200) and 97 (11.4%) had highest titers (1:204,800). Among the 2191 HIV-1 negative patients,
the prevalence of high anti-HHV-8 antibody titers (â„1:51,200) was independently associated with
increasing age (ptrend = 0.04), having a marital status of separated or divorced (p = 0.003), using
wood, coal or charcoal as fuel for cooking 20 years ago instead of electricity (p = 0.02) and
consuming traditional maize beer more than one time a week (p = 0.02; p-trend for increasing
consumption = 0.05) although this may be due to chance given the large number of predictors
considered in this analysis.
Conclusions: Among HIV-negative subjects, patients with high anti-HHV-8 antibody titers are
characterized by older age. Other associations that may be factors in the development of high anti-
HHV-8 titers include exposure to poverty or a low socioeconomic status environment and
consumption of traditional maize beer. The relationship between these variables and high anti-
HHV-8 titers requires further, prospective study
Business School Partnerships for Globalization
International partnerships are an essential tool to enable business schools to internationalize their activities. They can lead to improved research, better more internationally relevant teaching, provide staff with an international perspective, and help prepare students for careers in global business. Using case studies of four of Durham University Business School's main partnerships, the article identifies the motivations for forming partnerships, examines some of the practical management issues associated with partnership working in higher education, and details the many benefits that can be derived from such arrangements
Aquilegia, Vol. 15 No. 5, September-October 1991: Newsletter of the Colorado Native Plant Society
https://epublications.regis.edu/aquilegia/1060/thumbnail.jp
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